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Pharmaceutical raw material powder Pain killer Procaine HCl dosage effect

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Pharmaceutical raw material powder Pain killer Procaine HCl dosage effect

China Pharmaceutical raw material powder Pain killer Procaine HCl dosage effect supplier

Large Image :  Pharmaceutical raw material powder Pain killer Procaine HCl dosage effect

Product Details:

Place of Origin: China
Brand Name: Yuancheng
Certification: Iso9001
Model Number: 51-05-8

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: Discreet ways of packing for Customs pass guaranteed
Delivery Time: within 24hours after payment
Payment Terms: Western Union, T/T, MoneyGram, Bitcoin
Supply Ability: Plenty of stock
Detailed Product Description
Product Name: Procaine HCL Assay: 99%
CAS No.: 51-05-8 EINECS: 200-077-2
MF: C13H21ClN2O2 MW: 272.77
Melting Point: 155-156 °C Grade: Pharmaceutical Grade
Storage: Shading, Confined Preservation Appearance: White Crystalline Powder
Alias: Neocaine Anadolor Aminocaine Key Word: Local Anesthetics
Usage: Pain Killer

Pharmaceutical raw material powder Pain killer Procaine HCl dosage effect 

 

Quick detail

 

Product name: Procaine hydrochloride ;Procaine HCl
Synonyms:aminocaine;anadolor;anesthesol;anestil;atoxicocaine;Benzoicacid,4-amino-,2-(diethylamino)ethylester,monohydrochloride;benzoicacid,p-amino-,2-(diethylamino)ethylester,monohydrochloride;bernocaine
CAS:51-05-8
MF:C13H21ClN2O2
MW:272.77
EINECS:200-077-2
Categories:Pharmaceutical;Anesthetics;Pharmaceutical intermediate
Appearance:white crystalline powder
Assay:99.5%
Usage:Local anesthesic ;Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.

 

 

Related products:

 

Benzocaine base: / benzocaine /benzocaine/ procaine / lidocaine / lidocaie hcl / procaine hcl

 

Produt name:
Benzocaine Powder
Purity: 99.5%
CAS No.: 94-09-7
Appearance: White Crystal Powder
Usage: Local anesthetic.
Standard: USP/BP standard

 

Lidocaine base
Chemical Name: Lidocaine
Molecular Formula: C14H22N2O
Formula Weight: 234.34
CAS No.: 137-58-6
Pakcage: 25kg/drum
Usage: Local anesthetics

 

Peoduct name: Lidocaine hydrochloride
Cas: 73-78-9
MF: C14H23ClN2O
MW: 270.7982
Melting point: 350.8° C at 760 mmHg
Usage: Local anesthetics, antiarrhythmic drugs, used for a variety of anesthesia and rapid ventricular arrhythmia

 

Procaine
Product name: Procaine
CAS No.: 59-46-1
MF: C13H20N2O2
MW: 236.31
Purity: 99%
Appearance: White Crystalline Powder
Place of Origin: China
Standard: USP
Usage: Local anesthetics

 

3. Procaine HCl Specification

 

Product name Procaine HCl
Appearance White crystalline powder
Assay (C13H20N2O2¡¤HCl) 99.0% to 101.0% 99.5%
Melting point 153~158ºC 156.5~157.0ºC
Heavy metals ≤20ppm <5ppm
Acidity ≤0.02N NaOH 0.5ml 0.3ml
Chromatographic purity Secondary spots≤0.5%,sum≤1.0% Conforms
Loss on drying ≤1.0% 0.06%
Residue on ignition ≤0.15% 0.03%
Bacterial endotoxins ≤0.6EU/mg <0.6EU/mg

 

 

Procaine hydrochloride Description

 

Prasaine hydrochloride is a local anesthetic, can temporarily block the nerve fiber conduction and anesthesia, the role of strong, low toxicity, no addiction, but the skin, mucosal permeability is weak, not suitable for surface anesthesia, the main clinical use In infiltration, spinal cord and conduction anesthesia.

 

White needle crystal or crystalline powder at room temperature odorless, bitter bitter bitter, soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. Ester chain in the pracaine hydrochloride structure can be hydrolyzed to produce amino acids and diethylamino ethanol, under certain conditions, p-aminobenzoic acid can be further decarboxylation to produce toxic aniline.

 

The structure of procaine hydrochloride with aromatic primary amino groups, easy to oxidize discoloration of pH, temperature, UV, oxygen and metal ions can accelerate oxidative discoloration. The aqueous solution was stable in pH 3.0 to 5. Therefore, the preparation of procaine hydrochloride injection usually need to add acid to adjust pH 3.3 ~ 5.5, strictly control the sterilization temperature and time. To 100 ℃ steam sterilization 30min cycle is appropriate, and should pay attention to the shadow, sealed to save.

 

The product structure of the aromatic primary amino group in the dilute hydrochloric acid can produce the diazonium salt of sodium nitrite. When the basic naphthol is added, the coupling reaction occurs and the azo compound is scarlet.

 

Procaine hydrochloride Usage

 

Procaine HCl is a local anesthetic drug for amino ester groups. It is mainly used to reduce intramuscular injection of penicillin pain, can also be used for dental use. As the merchandise name Novocain is everywhere, in some areas procaine is often referred to as Novak. Its main role is sodium channel blockers. Because of their sympathy, anti-inflammatory, perfusion enhancement and emotional enhancement, in some countries are used for treatment.

 

The application of procaine leads to inhibition of neuronal activity. Depression makes the nervous system become allergic, causing anxiety and vibration, leading to mild to severe convulsions. Studies of animals have shown that the use of procaine causes an increase in dopamine and serotonin levels in the brain. Other problems may vary depending on the individual's tolerance to procaine dose. Central nervous system excitation can cause tension and dizziness, if excessive coordination may lead to respiratory failure. Procaine may also cause myocardial ischemia leading to cardiac arrest.

 

Procaine can also cause allergic reactions, leading to individual breathing, rash and swelling problems. The allergic reaction to procaine is usually not for procaine itself, but its metabolite, PABA. Approximately one of about 3,000 people has an atypical form of pseudo-alkaline esterase, which does not require hydrolysis of anesthetic, such as procaine, resulting in increased levels of narcotics in the blood and increased toxicity.

 

Procaine hydrochloride discovery and use

 

Pracaine hydrochloride was first synthesized by the German chemist Albert Einhorn in 1905. He is looking for a can be used as anesthetic, non-toxic, no side effects, no addiction compounds. Dr. Eindhoven is looking for a compound that can replace cocaine as an anesthetic. Cocaine is used as an anesthetic. However, since cocaine is toxic, addictive, destructive to the central nervous system, its use is illegal. Dr. Einhorn was able to produce a compound that showed the property he was looking for. This new compound is called procaine.

 

"Pro" refers to a substitute, "cocaine" comes from the word cocaine. Because these names are similar, because they are anesthetized, the nature of procaine has a lot of confusion. Sporaine acts as an anesthetic when injected into muscle, but when combined as a compound, procaine is used as a vitamin. The procaine hydrochloride solution used as an anesthetic is called Norcaine.

 

Packaging & Delivery

1. Professional team for package and shipment.Special way to ship 100grams to 100kg powders at one time to your country

 

2. Fast and discreet shipment could be arranged for customs pass Guaranteed.

 

3. Tracking code 24 hours for customs pass guaranteed.

 

4. Many kinds of shipment, also can be as your requirement.

 

 

Our Advantage

 

1. Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.

 

2. We have a more profound professional knowledge, you can do a full range of services.

 

3. Great quality,favorable price and safe transport.

 

4. Secure and discreet shipment.

5. Parcel can be sent out in 24 hours after payment, express delivery with DHL,EMS,HKEMS,TNT,UPS,Fedex and 24h after-sales service.

 

Welcome to our online store , please feel free to contact me if you're interested in our items . We are a big preffesional supplier in China ,there are high quality raw powders , painless injectable oils and pharmaceutical peptides . Wholesale

price will be sent to you when you want to make long term business with us . Special package picture and uniue channel will share with you within our cooperations ,10kg ,25kg and more powders are available from us to send .

 

 

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